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Psoriatic arthritis : ウィキペディア英語版
Psoriatic arthritis

Psoriatic arthritis (also arthritis psoriatica, arthropathic psoriasis or psoriatic arthropathy) is a type of inflammatory arthritis that will develop in up to 30 percent of people who have the chronic skin condition psoriasis. Psoriatic arthritis is classified as a seronegative spondyloarthropathy and therefore occurs more commonly in patients with tissue type HLA-B27.
==Signs and symptoms==

* Pain, swelling, or stiffness in one or more joints is commonly present.
*
* Asymmetrical oligoarthritis (70%) (Involvement of the distal interphalangeal joints (DIP) is a characteristic feature).
*
* Sacroiliitis/spondylitis (40%)
*
* Symmetrical seronegative arthritis (15%)
*
* Distal interphalangeal joint arthritis (15%)
* Hand joints involved in psoriasis are proximal interphalangeal (PIP) + distal interphalangeal (DIP) + metacarpophalangeal (MCP) + wrist
* Joints that are red or warm to the touch.〔
* Sausage-like swelling in the fingers or toes, known as dactylitis.〔
* Pain in and around the feet and ankles, especially tendinitis in the Achilles tendon or plantar fasciitis in the sole of the foot.〔
* Changes to the nails, such as pitting or separation from the nail bed.〔
* Pain in the area of the sacrum (the lower back, above the tailbone).〔
* Along with the above noted pain and inflammation, there is extreme exhaustion that does not go away with adequate rest. The exhaustion may last for days or weeks without abatement. Psoriatic arthritis may remain mild, or may progress to more destructive joint disease. Periods of active disease, or flares, will typically alternate with periods of remission. In severe forms, psoriatic arthritis may progress to arthritis mutilans which on X-ray gives pencil in cup appearance.
* Because prolonged inflammation can lead to joint damage, early diagnosis and treatment to slow or prevent joint damage is recommended.
* Scaly skin lesions are seen over extensor surfaces (scalp, natal cleft and umbilicus).
* The nail changes are pitting, onycholysis, sub–ungual hyperkeratosis and horizontal ridging.〔(【引用サイトリンク】url=https://www.arthritisaction.org.uk/living/psoriatic_arthritis )

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Psoriatic arthritis」の詳細全文を読む



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